HUMAN EXPOSURE ASSESSMENT An Introduction
نویسندگان
چکیده
The views expressed in documents by named authors are solely the responsibility of those authors. The illustrations of the cover page are from the WHO photo library. III Preface T his book is part of a World Health Organization (WHO) series on teaching material and provides an introduction to the basic principles and methods of human exposure assessment. It constitutes a complement to Basic Epidemiology by Beaglehole et al (1993), and to Environmental Epidemiology (Baker et al, 1999), previously published by WHO. The textbook is intended for use in training courses, but also includes some fundamental information for the interested reader. The target groups are: • Environmental medicine and epidemiology students • Environmental and occupational health professionals • Risk management professionals • People with a basic knowledge of environmental health and epidemiology • Chemists, engineers and students of life-sciences The purpose of this book is to present basic knowledge about human exposure assessment and how it relates to other scientific specialities involved in public health protection. The overall aim of human exposure assessment is to promote and protect public health. It comprises all the methods available to describe, estimate and determine, qualitatively and quantitatively, people's contact with hazardous agents. The character of exposure assessment is multidisciplinary and therefore involves experts from various fields of science. Human exposure assessment plays an important role in epidemiology, risk assessment and risk management, as well as in status and trend analysis. The science of human exposure assessment is a growing field and this textbook offers references to more in-depth books and reviews which are provided at the end of this book (Chapter 10: Continuing your education). The World Health Organization and the United Nations Environment Programme (UNEP) have been promoting improved human exposure assessment through various activities for more than 20 years. One of these activities was the Human Exposure Assessment Location (HEAL) project which was implemented by WHO and UNEP with support from US EPA, the Japanese Government and other national agencies and which ran for more than 10 years (UNEP/WHO, 1986). The HEAL project was initiated to promote international collaboration in development and harmonisation of exposure assessment methodology and quality assurance activities. T IV In 1995, in response to the recommendations from the United Nations Conference on Environment and Development (UNCED) held in Rio de Janeiro 1992, the HEAL project was reorientated. The emphasis is now on the preparation of training and …
منابع مشابه
DEVELOPMENT OF A PHYSIOLOGICALLY BASED TOXICOKINETIC MODEL FOR HUMAN EXPOSURE RISK ASSESSMENT OF METHYLENE DIPHENYL DIISOCYANATE(MDI)
Introduction: Given the lack of a developed physiologically based toxicokinetic (PBTK) model for human systemic exposure assessment of methylene diisocyanate (MDI) and prediction of its urinary metabolites, this study aims to develop a PBTK model for exposure risk assessment of MDI. Methods and Materials: In this study, to assess the potential exposure to the MDI, a PBTK model was constructed ...
متن کاملCancer Risk Assessment due to Accidental Exposure inside Neutron Laboratories using BEIR VII Model
Introduction: Environmental and occupational human exposure from neutron source can lead to the serious biologic effects. The aim of this study is to evaluate the cancer incidence risk for various human organs at different neutron dose levels due to exposure from an Americium-241/Beryllium (Am-241/Be), a standard neutron source for calibration purposes. Material and Methods: We measured ambient...
متن کاملExposure Assessment to Environmental Pollutants in Human Health Risk Assessment Studies; Overview on New Approaches
Background & objectives: Because of human exposure to various environmental risk factors during the lifetime, the actual exposure estimation has been considered as one of the most important challenges for researchers and decision makers. Considering the contribution of environmental risk factors in the burden of diseases, this study aimed to provide new approaches in exposure assessment filed b...
متن کاملOccupational monitoring and health risks assessment of respiratory exposure to dust in an industrial unit of production Khak-e-Chini
Introduction: The respiratory system, as one of the most important organs of the human body, is affected by adverse health effects and consequences of particulate matter. this study was performed to purpose determine the occupational exposure of workers to crystalline silica of inhalable dust and determine its health risks. Method: In this analytical cross-sectional study, sampling was perform...
متن کاملSemi-quantitative risk assessment of occupational exposure area industrial wastewater Treatment unit in an oil refinery and chemical contaminants
Background and aims: The chemical pollution in industries has make an unacceptable risk for the human health. For the risk assessment of the human exposure, it is necessary to be considered the material dangers based on the consumption rate, dose, toxic properties, and evaluation of potential effects on the human health. Therefore, the aim of this study was to assess the semi-quantitative risk ...
متن کاملDetermine the average score of skin exposure to chemotherapy drugs in oncology staffs at hospitals and health services of Shahid Sadoughi university of medical Sciences and health Services by DREAM method in 2015
Introduction: Occupational Dermal exposure to Antineoplastic Drugs is the one of the most important routes in Healthcare staffs. Several antineoplastic drugs have been classified as carcinogens by the International Agency for Research on Cancer (IARC). Regards to this issue investigation on Dermal exposure to Antineplastic Drugs in healthcare staffs is nessessary. Method: In this Descriptive a...
متن کامل